Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.36 |
| ▸ | MERTK | Q12866 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PDE5A | O76074 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.32 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11099340 | 0.80 | GRIA1 (0.43) | PDPK1MERTKTSHRMAPK1MAPT | |
| SCHEMBL693898 | 0.69 | CHKA (0.42) | MAPK1L3MBTL1PDE5AGSK3BEGFR | |
| SCHEMBL5842734 | 0.68 | CRHR1 (0.37) | TSHRMAPK1L3MBTL1KDM4E | |
| SCHEMBL758648 | 0.68 | LMNA (0.50) | CYP1A2CYP2D6CYP2C19NUDT1KDM4E | |
| SCHEMBL8974883 | 0.63 | TSHR (0.53) | MERTKCYP1A2CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL3117685 | 0.62 | PDE5A (0.66) | PDE5AEGFRPDGFRBKDR | |
| SCHEMBL7835867 | 0.62 | SIGMAR1 (0.49) | CYP1A2CYP2D6CYP2C19MAPTKDM4E | |
| SCHEMBL3385311 | 0.61 | HDAC1 (0.47) | CYP1A2CYP3A4CYP2D6CYP2C9TSHR | |
| Hydrochloric Acid SCHEMBL9776928 | 0.61 | PDE5A (0.67) | PDE5AEGFRPDGFRBKDR | |
| Hydrochloric Acid SCHEMBL9776742 | 0.61 | PDE5A (0.67) | PDE5AEGFRPDGFRBKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4310347-A | Herbicidal 1,2,4-benzotriazines | ICI AUSTRALIA LIMITED (AU) | 1982-01-12 | — | — | US | disclosed |