Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.39 |
| ▸ | BCHE | P06276 | 10/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11070774 | 0.84 | CYP3A4 (0.45) | ACHEOPRM1OPRL1CYP3A4LMNA | |
| SCHEMBL11556186 | 0.82 | OPRM1 (0.40) | OPRM1OPRL1ALDH1A1OPRD1OPRK1 | |
| SCHEMBL11092425 | 0.81 | CYP3A4 (0.38) | ACHEBCHEOPRM1OPRL1CYP3A4 | |
| Ethylene SCHEMBL11554547 | 0.80 | OPRM1 (0.38) | OPRM1OPRL1ALDH1A1OPRD1OPRK1 | |
| SCHEMBL11099343 | 0.78 | ACHE (0.40) | ACHEOPRM1OPRL1CYP3A4LMNA | |
| SCHEMBL11093289 | 0.78 | ALDH1A1 (0.41) | ACHEOPRM1CYP3A4LMNAALDH1A1 | |
| SCHEMBL11088920 | 0.77 | CYP3A4 (0.39) | ACHEOPRM1OPRL1CYP3A4LMNA | |
| SCHEMBL11075750 | 0.75 | OPRM1 (0.46) | ACHEOPRM1OPRL1CYP3A4LMNA | |
| SCHEMBL11097716 | 0.74 | OPRM1 (0.43) | ACHEOPRM1OPRL1CYP3A4LMNA | |
| Hydrochloric Acid SCHEMBL11099770 | 0.74 | OPRM1 (0.45) | ACHEOPRM1OPRL1CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4460604-A | ANALGESICS, NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| US-4180584-A | ANALGESIC; NARCOTIC ANTAGONIST | THE UPJOHN COMPANY (US) | 1979-12-25 | — | — | US | disclosed |
| US-4065573-A | ANALGESICS | THE UPJOHN COMPANY (US) | 1977-12-27 | — | — | US | disclosed |