Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | FDPS | P14324 | 1/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP2 | P08253 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11126584 | 0.78 | MMP8 (0.42) | AHRTP53MAPK1TDP1ALDH1A1 | |
| SCHEMBL11604324 | 0.76 | HPGD (0.46) | AHRTP53MAPK1TDP1ALDH1A1 | |
| SCHEMBL1775211 | 0.76 | MMP8 (0.46) | AHRTP53MAPK1TDP1ALDH1A1 | |
| SCHEMBL11099508 | 0.70 | ALDH1A1 (0.39) | TDP1ALDH1A1TSHRMEN1NPC1 | |
| SCHEMBL10931270 | 0.67 | HSD17B10 (0.42) | AHRTP53MAPK1TDP1ALDH1A1 | |
| SCHEMBL11777105 | 0.66 | FDPS (0.44) | ALDH1A1MMP8MMP14CA14TSHR | |
| SCHEMBL11100457 | 0.62 | TPMT (0.35) | MMP8MMP1MMP2 | |
| SCHEMBL11795326 | 0.62 | LMNA (0.44) | MAPK1ALDH1A1MMP8MMP14CA14 | |
| SCHEMBL14337806 | 0.62 | HPGD (0.59) | TDP1ALDH1A1MMP8TSHRCYP3A4 | |
| Phosphoric Acid SCHEMBL28200084 | 0.60 | TP53 (0.64) | TP53TDP1ALDH1A1MMP8MMP14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0019401-B1 | PROCESS FOR PREPARING ENAMINE DERIVATIVES, COMPOUNDS SO PRODUCED AND PROCESS FOR PREPARING A 3-HYDROXY-CEPHALOSPORIN | Lilly Industries Limited (GB) | 1984-03-21 | — | — | EP | disclosed |
| US-4301280-A | Preparation of 3-substituted cephalosporins | LILLY INDUSTRIES LIMITED (GB) | 1981-11-17 | — | — | US | disclosed |
| EP-0019401-A1 | Process for preparing enamine derivatives, compounds so produced and process for preparing a 3-hydroxy-cephalosporin | Lilly Industries Limited (GB) | 1980-11-26 | — | — | EP | disclosed |