Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 3/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.42 |
| ▸ | MGLL | Q99685 | 3/20 | 0.42 |
| ▸ | FAAH | O00519 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | TNF | P01375 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | GBA1 | P04062 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.40 |
| ▸ | RGS4 | P49798 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12787622 | 0.83 | MGLL (0.52) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL4963710 | 0.83 | MGLL (0.52) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL9626274 | 0.83 | MGLL (0.52) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL11840543 | 0.83 | MGLL (0.52) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL6239660 | 0.80 | RGS4 (0.50) | PTGS1PTGS2MGLLFAAHTNF | |
| SCHEMBL10014291 | 0.77 | ADORA2B (0.47) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL23509686 | 0.74 | RGS4 (0.44) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL10382375 | 0.74 | RGS4 (0.45) | PTGS1PTGS2MGLLFAAHALDH1A1 | |
| SCHEMBL13327050 | 0.73 | ALDH1A1 (0.42) | MGLLFAAHALDH1A1HSD17B10TP53 | |
| SCHEMBL25465030 | 0.73 | ALDH1A1 (0.42) | MGLLFAAHALDH1A1HSD17B10TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044420-B1 | HYDROXYALKYL-1,2,4-TRIAZOLIDINE-3,5-DIONES AND PROCESS FOR THEIR PREPARATION | BAYER AG (DE) | 1984-11-28 | — | — | EP | disclosed |
| US-4377694-A | CROSSLINKER, ACTIVATOR FOR POLYESTERS, POLYETHERS, OR POLYURETHANES | BAYER AKTIENGESELLSCHAFT (DE) | 1983-03-22 | — | — | US | disclosed |
| EP-0044420-A1 | Hydroxyalkyl-1,2,4-triazolidine-3,5-diones and process for their preparation | BAYER AG (DE) | 1982-01-27 | — | — | EP | disclosed |