Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11105252 | 0.88 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2C8CYP2C9CYP2B6 | |
| SCHEMBL11101082 | 0.88 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2C8CYP2C9CYP2B6 | |
| SCHEMBL2351166 | 0.82 | ALDH1A1 (0.54) | CYP1A2CYP3A4CYP2C8CYP2C9CYP2B6 | |
| SCHEMBL12049711 | 0.82 | — | — | |
| SCHEMBL9320263 | 0.82 | THRA (0.43) | — | |
| SCHEMBL9321693 | 0.82 | THRA (0.43) | — | |
| SCHEMBL14601748 | 0.80 | CYP1A2 (0.53) | CYP1A2CYP3A4CYP2C8CYP2C9CYP2B6 | |
| SCHEMBL4000923 | 0.79 | CNR2 (0.62) | CYP1A2CYP3A4CYP2C8CYP2C9CYP2B6 | |
| SCHEMBL28400947 | 0.79 | CYP3A4 (0.65) | CYP1A2CYP3A4CYP2C8CYP2C9CYP2B6 | |
| SCHEMBL28386231 | 0.79 | CYP3A4 (0.65) | CYP1A2CYP3A4CYP2C8CYP2C9CYP2B6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443473-A | ANALGESICS, ANTIALLERGENS | THE PROCTER & GAMBLE COMPANY (US) | 1984-04-17 | — | — | US | disclosed |