Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9321693 | 1.00 | THRA (0.43) | THRATHRBS1PR2S1PR1S1PR3 | |
| SCHEMBL9320972 | 0.94 | EPHX2 (0.43) | THRATHRB | |
| SCHEMBL9321717 | 0.89 | THRA (0.47) | THRATHRBS1PR2S1PR1S1PR3 | |
| SCHEMBL9320996 | 0.89 | THRA (0.47) | THRATHRBS1PR2S1PR1S1PR3 | |
| SCHEMBL9320967 | 0.84 | EPHX2 (0.47) | THRATHRB | |
| SCHEMBL11099994 | 0.82 | CYP1A2 (0.51) | — | |
| SCHEMBL9320976 | 0.81 | LTA4H (0.42) | S1PR2S1PR1S1PR3LPAR2 | |
| SCHEMBL9323114 | 0.77 | QPCT (0.49) | — | |
| SCHEMBL6472270 | 0.76 | MEN1 (0.56) | — | |
| SCHEMBL9320317 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0282127-B1 | Beta-aminoethyl-substituted phenyl compounds, and anti-inflammatory or analgesic compositions containing them | PROCTER & GAMBLE (US) | 1994-02-02 | — | — | EP | disclosed |
| US-5099030-A | Phenols or phenolic ethers | THE PROCTER & GAMBLE COMPANY (US) | 1992-03-24 | — | — | US | disclosed |
| US-5045565-A | Novel compounds, pharmaceutical compositions, and methods for treating inflammation and pain | THE PROCTER & GAMBLE COMPANY (US) | 1991-09-03 | — | — | US | disclosed |