SCHEMBL11101082

SCHEMBL11101082

CCCCCCCCCCCCN(Cc1ccc(O)c(OC)c1)C(=O)O

nearest known ligand 0.63

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.57
CYP3A4 P08684 2/20 0.57
CYP2C9 P11712 2/20 0.57
CYP2C19 P33261 2/20 0.57
CYP2C8 P10632 1/20 0.57
CYP2B6 P20813 1/20 0.57
ALDH1A1 P00352 1/20 0.55
CYP2D6 P10635 1/20 0.55
HPGD P15428 1/20 0.55
ALOX15 P16050 1/20 0.55
BLM P54132 1/20 0.55
PMP22 Q01453 1/20 0.55
TRPV1 Q8NER1 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11105252 1.00 CYP1A2 (0.57) CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8
SCHEMBL2351166 0.95 ALDH1A1 (0.54) CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8
SCHEMBL11099994 0.88 CYP1A2 (0.51) CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8
SCHEMBL4000923 0.86 CNR2 (0.62) CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8
SCHEMBL28400947 0.84 CYP3A4 (0.65) CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8
SCHEMBL28386231 0.84 CYP3A4 (0.65) CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8
SCHEMBL9321717 0.82 THRA (0.47)
SCHEMBL9320996 0.82 THRA (0.47)
SCHEMBL11098754 0.81 GAA (0.59) ALDH1A1TRPV1
SCHEMBL12802444 0.81 CYP1A2 (0.55) CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4443473-A ANALGESICS, ANTIALLERGENS THE PROCTER & GAMBLE COMPANY (US) 1984-04-17 US disclosed