Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | POLB | P06746 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29582442 | 1.00 | MAPT (0.56) | MAPTALDH1A1POLBL3MBTL1HCRTR1 | |
| SCHEMBL30278836 | 0.85 | GPR3 (0.50) | MAPTALDH1A1POLBL3MBTL1HCRTR1 | |
| SCHEMBL13021657 | 0.85 | GPR3 (0.50) | MAPTALDH1A1POLBL3MBTL1HCRTR1 | |
| SCHEMBL1042694 | 0.82 | MAPT (0.64) | MAPTALDH1A1POLBL3MBTL1HCRTR1 | |
| SCHEMBL8086595 | 0.81 | ALDH1A1 (0.63) | MAPTALDH1A1POLBL3MBTL1HCRTR1 | |
| SCHEMBL10059336 | 0.79 | MAPT (0.58) | MAPTALDH1A1POLBL3MBTL1HCRTR1 | |
| SCHEMBL29402827 | 0.76 | MAPT (0.63) | MAPTALDH1A1POLBL3MBTL1HCRTR1 | |
| SCHEMBL530095 | 0.76 | MAPT (0.63) | MAPTALDH1A1POLBL3MBTL1HCRTR1 | |
| SCHEMBL30161811 | 0.76 | ALDH1A1 (0.64) | MAPTALDH1A1POLBL3MBTL1HCRTR1 | |
| SCHEMBL3483642 | 0.76 | ALDH1A1 (0.64) | MAPTALDH1A1POLBL3MBTL1HCRTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0110832-A1 | Xanthene-9-ones and thioxanthene-9-ones | CIBA-GEIGY AG (CH) | 1984-06-13 | — | — | EP | disclosed |