Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.55 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | BLM | P54132 | 1/20 | 0.53 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.53 |
| ▸ | HTR1A | P08908 | 2/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12802675 | 1.00 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL12802835 | 1.00 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL12802951 | 1.00 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL12803008 | 0.85 | TSHR (0.54) | CYP1A2CYP3A4ALDH1A1BLM | |
| SCHEMBL12803112 | 0.81 | CYP3A4 (0.45) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL11101082 | 0.81 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL11105252 | 0.81 | CYP1A2 (0.57) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL2945289 | 0.79 | TSHR (0.47) | CYP3A4ALDH1A1 | |
| SCHEMBL12802673 | 0.79 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 | |
| SCHEMBL12802565 | 0.79 | CYP1A2 (0.55) | CYP1A2CYP3A4CYP2C9CYP2C19CYP2C8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9422233-B2 | Vanilloid fatty hydroxamates as therapeutic anti-inflammatory pharmaceuticals | RUTGERS, THE STATE UNIVERSITY OF NEW JERSEY (US) | 2016-08-23 | — | — | US | disclosed |
| US-20120252891-A1 | Vanilloid Fatty Hydroxamates as Therapeutic Anti-inflammatory Pharmaceuticals | UNIVERSITY OF MEDICINE AND DENTISTRY OF NEW JERSEY (US) | 2012-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120252891-A1 | Vanilloid Fatty Hydroxamates as Therapeutic Anti-inflammatory Pharmaceuticals | FAAH, FAAH2, TRPV1 | CYP1A2 1825/4885CYP3A4 1025/4885CYP2C9 390/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.