Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CPT1A | P50416 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2053494 | 0.86 | HTT (0.70) | KDM4EALDH1A1LMNAHSD17B10HPGD | |
| Hydrochloric Acid SCHEMBL7514852 | 0.85 | HTT (0.68) | KDM4EALDH1A1LMNAHSD17B10HPGD | |
| SCHEMBL29950498 | 0.82 | LMNA (0.64) | KDM4EALDH1A1LMNAHSD17B10HPGD | |
| SCHEMBL3477919 | 0.82 | KDM4E (0.64) | KDM4EALDH1A1LMNAHSD17B10HPGD | |
| SCHEMBL28289149 | 0.81 | SMN1; SMN2 (0.62) | KDM4EALDH1A1LMNAHSD17B10HPGD | |
| SCHEMBL28872023 | 0.80 | KDM4E (0.61) | KDM4EALDH1A1LMNAHSD17B10HPGD | |
| SCHEMBL592889 | 0.80 | NR4A2 (0.77) | KDM4EALDH1A1LMNAHSD17B10HPGD | |
| SCHEMBL1558974 | 0.79 | NR4A2 (0.71) | KDM4EALDH1A1LMNAHSD17B10HPGD | |
| SCHEMBL9725707 | 0.79 | LMNA (0.64) | KDM4EALDH1A1LMNAHSD17B10HPGD | |
| SCHEMBL3847939 | 0.78 | GABRA1 (0.73) | KDM4EALDH1A1LMNAHSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0055068-B1 | QUINOLONE DERIVATIVES AND THEIR USE AS PHARMACEUTICALS | Lilly Industries Limited (GB) | 1984-10-17 | — | — | EP | disclosed |
| US-4390541-A | ANTIALLERGENS; ANTISPASMODIC AGENTS | LILLY INDUSTRIES LIMITED (GB) | 1983-06-28 | — | — | US | disclosed |
| EP-0055068-A1 | Quinolone derivatives and their use as pharmaceuticals | Lilly Industries Limited (GB) | 1982-06-30 | — | — | EP | disclosed |