Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.64 |
| ▸ | MEN1 | O00255 | 2/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.64 |
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | MITF | O75030 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.63 |
| ▸ | GABRA1 | P14867 | 8/20 | 0.61 |
| ▸ | GABRB2 | P47870 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.59 |
| ▸ | CPT1A | P50416 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2053494 | 0.83 | HTT (0.70) | LMNAMEN1KMT2AMAPTMITF | |
| SCHEMBL3847939 | 0.83 | GABRA1 (0.73) | LMNAMEN1KMT2AMAPTMITF | |
| SCHEMBL3477919 | 0.82 | KDM4E (0.64) | LMNAMEN1KMT2AMAPTMITF | |
| SCHEMBL29950498 | 0.82 | LMNA (0.64) | LMNAMEN1KMT2AMAPTMITF | |
| Hydrochloric Acid SCHEMBL7514852 | 0.82 | HTT (0.68) | LMNAMEN1KMT2AMAPTMITF | |
| SCHEMBL8558972 | 0.80 | LMNA (0.82) | LMNAMEN1KMT2AMAPTMITF | |
| SCHEMBL10566584 | 0.80 | MEN1 (0.73) | LMNAMEN1KMT2AMAPTMITF | |
| SCHEMBL28872023 | 0.80 | KDM4E (0.61) | LMNAMEN1KMT2AMAPTMITF | |
| SCHEMBL11101264 | 0.79 | KDM4E (0.60) | LMNAMEN1KMT2AMAPTMITF | |
| SCHEMBL8556745 | 0.78 | LMNA (0.78) | LMNAMEN1KMT2AMAPTMITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143920-A | Antiulcer, antisecretory | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1992-09-01 | — | — | US | disclosed |
| EP-0342775-A1 | 4-Amino-3-acylquinoline derivatives and their use as inhibitors of gastric secretion | SMITHKLINE BEECHAM INTERCREDIT B.V. (NL) | 1989-11-23 | — | — | EP | disclosed |
| WO-1989008105-A1 | 4-AMINO-3-ACYLQUINOLINE DERIVATIVES AND THEIR USE AS INHIBITORS OF GASTRIC SECRETION | SMITHKLINE BECKMAN INTERCREDIT B.V. (NL) | 1989-09-08 | — | — | WO | disclosed |