Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.38 |
| ▸ | BRPF1 | P55201 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7119411 | 0.82 | KDM4E (0.55) | KDM4EALDH1A1HPGDBRD4L3MBTL1 | |
| SCHEMBL38573232 | 0.82 | KDM4E (0.55) | KDM4EALDH1A1HPGDBRD4L3MBTL1 | |
| SCHEMBL2845831 | 0.77 | IDO1 (0.48) | ALDH1A1HPGDTSHRCYP2C9 | |
| SCHEMBL14194047 | 0.73 | KDM4E (0.44) | KDM4EALDH1A1HPGDBRD4L3MBTL1 | |
| SCHEMBL15583274 | 0.73 | CNR2 (0.50) | KDM4EALDH1A1HPGDBRD4L3MBTL1 | |
| SCHEMBL14001880 | 0.73 | MEN1 (0.36) | KDM4EALDH1A1HPGDBRD4L3MBTL1 | |
| SCHEMBL10391045 | 0.73 | KDM4E (0.55) | KDM4EALDH1A1HPGDBRD4L3MBTL1 | |
| SCHEMBL2879124 | 0.73 | IDO1 (0.50) | KDM4ECYP2C9 | |
| SCHEMBL38471077 | 0.73 | KDM4E (0.55) | KDM4EALDH1A1HPGDBRD4L3MBTL1 | |
| SCHEMBL11058027 | 0.72 | MAPT (0.55) | KDM4EALDH1A1HPGDBRD4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2279291-B1 | COFERONS AND METHODS OF MAKING AND USING THEM | UNIV CORNELL (US) | 2019-07-03 | — | — | EP | disclosed |
| US-9943603-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| US-9943603-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2018-04-17 | — | — | US | disclosed |
| US-20150105553-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-04-16 | — | — | US | disclosed |
| US-8853185-B2 | Coferons and methods of making and using them | CORNELL UNIVERSITY (US) | 2014-10-07 | — | — | US | disclosed |
| US-20110263688-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | PURDUE RESEARCH FOUNDATION (US) | 2011-10-27 | — | — | US | disclosed |
| EP-2279291-A2 | COFERONS AND METHODS OF MAKING AND USING THEM | Cornell University (US) | 2011-02-02 | — | — | EP | disclosed |
| WO-2009126290-A2 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2009-10-15 | — | — | WO | disclosed |
| WO-2009126290-A2 | COFERONS AND METHODS OF MAKING AND USING THEM | CORNELL UNIVERSITY (US) | 2009-10-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150105553-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | MYOF, TNFSF11, F13B | KDM4E 4058/4885ALDH1A1 2898/4885HPGD 2895/4885 |
| US-20110263688-A1 | COFERONS AND METHODS OF MAKING AND USING THEM | MYOF, FTH1, TFRC | KDM4E 4076/4885ALDH1A1 3614/4885HPGD 1780/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.