Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | ACP3 | P15309 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2879124 | 0.94 | IDO1 (0.50) | IDO1CYP1A2CYP2C19CYP2C9CYP2D6 | |
| SCHEMBL11822029 | 0.88 | IDO1 (0.48) | IDO1CYP1A2CYP2C19CYP2C9TDP1 | |
| SCHEMBL28899 | 0.84 | CYP1A2 (0.58) | IDO1CYP1A2CYP2C19CYP2C9CYP2D6 | |
| SCHEMBL131470 | 0.82 | HPRT1 (0.58) | CYP1A2CYP2C19CYP2C9CYP2D6TDP1 | |
| SCHEMBL1110814 | 0.78 | KDM4E (0.35) | IDO1ALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL17756341 | 0.78 | IDO1 (0.41) | IDO1CYP1A2CYP2C19CYP2C9CYP2D6 | |
| SCHEMBL20710913 | 0.78 | IDO1 (0.36) | IDO1CYP1A2ALDH1A1HPGDHSD17B10 | |
| SCHEMBL12405309 | 0.77 | CHRM2 (0.34) | IDO1ALDH1A1 | |
| SCHEMBL1110135 | 0.77 | KDM4E (0.42) | CYP2C9ALDH1A1HPGDTSHR | |
| SCHEMBL29365799 | 0.76 | IDO1 (0.63) | IDO1CYP1A2CYP2D6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10344005-B2 | Synthesis of cyclophanes for a self-assembly reaction | UNIVERSITY OF OREGON (US) | 2019-07-09 | — | — | US | disclosed |
| US-9790192-B2 | Synthesis of cyclophanes from a self-assembly reaction | UNIVERSITY OF OREGON (US) | 2017-10-17 | — | — | US | disclosed |
| US-20160137598-A1 | SYNTHESIS OF CYCLOPHANES FROM A SELF-ASSEMBLY REACTION | UNIVERSITY OF OREGON (US) | 2016-05-19 | — | — | US | disclosed |
| US-20160137598-A1 | SYNTHESIS OF CYCLOPHANES FROM A SELF-ASSEMBLY REACTION | UNIVERSITY OF OREGON (US) | 2016-05-19 | — | — | US | disclosed |
| US-20100147768-A1 | RENEWABLE SORBENT MATERIAL AND METHOD OF USE | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF UNIVERSITY | 2010-06-17 | — | — | US | disclosed |
| US-20100147768-A1 | RENEWABLE SORBENT MATERIAL AND METHOD OF USE | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF UNIVERSITY | 2010-06-17 | — | — | US | disclosed |
| US-20100147768-A1 | RENEWABLE SORBENT MATERIAL AND METHOD OF USE | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF UNIVERSITY | 2010-06-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10344005-B2 | Synthesis of cyclophanes for a self-assembly reaction | TST, CTH, CBS | IDO1 1189/4885CYP1A2 721/4885CYP2C19 1602/4885 |
| US-20160137598-A1 | SYNTHESIS OF CYCLOPHANES FROM A SELF-ASSEMBLY REACTION | TST, CTH, CBS | IDO1 1121/4885CYP1A2 701/4885CYP2C19 1621/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.