Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 7/20 | 0.40 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.38 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.38 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11100203 | 0.98 | OPRM1 (0.47) | OPRM1OPRD1KCNH2BCHEHTR4 | |
| SCHEMBL12367439 | 0.78 | ENPP2 (0.38) | HTR4ALDH1A1 | |
| SCHEMBL24556400 | 0.77 | LMNA (0.50) | OPRM1OPRD1HTR4ALDH1A1 | |
| SCHEMBL11346977 | 0.76 | OPRM1 (0.40) | OPRM1OPRD1 | |
| SCHEMBL11102346 | 0.75 | POLB (0.38) | OPRM1KCNH2ALDH1A1S1PR1S1PR5 | |
| SCHEMBL2883737 | 0.73 | SLC6A3 (0.47) | OPRM1OPRD1ALDH1A1 | |
| Heptane SCHEMBL27728177 | 0.73 | PLG (0.48) | ALDH1A1S1PR1S1PR3S1PR4S1PR5 | |
| Hexadecane SCHEMBL28525033 | 0.73 | PLG (0.48) | ALDH1A1S1PR1S1PR3S1PR4S1PR5 | |
| Octane SCHEMBL28203894 | 0.73 | PLG (0.48) | ALDH1A1S1PR1S1PR3S1PR4S1PR5 | |
| Hydrochloric Acid SCHEMBL11100987 | 0.73 | TDP1 (0.38) | OPRM1KCNH2ALDH1A1S1PR1S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0031219-B1 | ANILINE DERIVATIVES | BEECHAM GROUP PLC (GB) | 1984-03-07 | — | — | EP | disclosed |
| US-4350691-A | ANTIEMETICS | BEECHAM GROUP LIMITED (GB) | 1982-09-21 | — | — | US | disclosed |
| EP-0031219-A1 | Aniline derivatives | BEECHAM GROUP PLC (GB) | 1981-07-01 | — | — | EP | disclosed |