SCHEMBL548012

SCHEMBL548012

CCCCCCCCCCC(=O)Oc1ccc2c(c1)CC[C@@H]1[C@@H]2CC[C@]2(C)[C@@H](O)CC[C@@H]12

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 7/20 0.73
ESR1 P03372 6/20 0.73
SMN1; SMN2 Q16637 5/20 0.73
ADORA3 P0DMS8 3/20 0.73
ATM Q13315 3/20 0.73
PGR P06401 3/20 0.73
AR P10275 3/20 0.73
CHRM1 P11229 2/20 0.73
TBXA2R P21731 2/20 0.73
SLC6A3 Q01959 2/20 0.73
ADRA1A P35348 1/20 0.73
OPRM1 P35372 1/20 0.73
KMT2A Q03164 5/20 0.67
NR3C1 P04150 2/20 0.67
SHBG P04278 2/20 0.67
SLC6A4 P31645 2/20 0.67
HTR2B P41595 2/20 0.67
FYN P06241 1/20 0.67
ADRA2C P18825 1/20 0.67
SLC6A2 P23975 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17419466 1.00 LMNA (0.73) LMNAESR1SMN1; SMN2ADORA3ATM
SCHEMBL1315380 1.00 LMNA (0.73) LMNAESR1SMN1; SMN2ADORA3ATM
SCHEMBL547938 1.00 LMNA (0.73) LMNAESR1SMN1; SMN2ADORA3ATM
SCHEMBL17419453 1.00 LMNA (0.73) LMNAESR1SMN1; SMN2ADORA3ATM
Estradiol Acetate SCHEMBL547226 0.97 LMNA (0.80) LMNAESR1SMN1; SMN2ADORA3ATM
SCHEMBL4333126 0.96 LMNA (0.75) LMNAESR1SMN1; SMN2ADORA3ATM
SCHEMBL40564 0.96 LMNA (0.75) LMNAESR1SMN1; SMN2ADORA3ATM
SCHEMBL11102416 0.96 LMNA (0.75) LMNAESR1SMN1; SMN2ADORA3ATM
SCHEMBL9404736 0.94 LMNA (0.77) LMNAESR1SMN1; SMN2ADORA3ATM
SCHEMBL7633202 0.93 LMNA (0.73) LMNAESR1SMN1; SMN2ADORA3ATM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 499 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12310928-B2 Enthesis healing UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2025-05-27 US claimed
US-20240315965-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2024-09-26 US claimed
EP-3863708-B1 MIXED IONIC CONDUCTORS AND CORRESPONDING DEVICES, SYSTEMS AND METHODS OF MAKING BATTELLE MEMORIAL INSTITUTE (US) 2024-09-11 EP claimed
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2023-03-23 US claimed
WO-2022182527-A1 COMPOSITIONS AND METHODS RELATED TO PHARMACEUTICAL EXCIPIENTS Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2022182523-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2022-09-01 WO claimed
WO-2021158573-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO claimed
WO-2021158575-A1 COMPOSITIONS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES Natural Extraction Systems, LLC (US) 2021-08-12 WO claimed
US-20180305742-A1 USE OF ESTROGENIC COMPOUNDS TO MANIPULATE THE BACTERIAL COMPOSITION OF VAGINAL COMMUNITIES UNIVERSITY OF IDAHO (US) 2018-10-25 US claimed
US-8110565-B2 Of the ACE inhibitor ramipril; controlling the melting point by mixing with the free acid with the ramipril ethyl or methyl ester prodrug and a pressure sensitive adhesive carrier; improved pharmacokinetics; sustained release NOVEN PHARMACEUTICALS, INC. (US) 2012-02-07 US claimed
WO-1997047324-A1 METHOD OF USING ALOE VERA AS A BIOLOGICAL VEHICLE UNIVERA PHARMACEUTICALS, INC. (US) 1997-12-18 WO claimed
EP-0346014-B1 Therapeutic product for the treatment of peri- or postmenopausal conditions ZENECA LTD (GB) 1994-08-03 EP claimed
US-5183814-A Administering estrogen and antiestrogen IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1993-02-02 US claimed
EP-0256668-B1 METHOD FOR TREATING MALE SEXUAL DYSFUNCTION UNIVERSITY OF FLORIDA (US) 1992-11-04 EP claimed
EP-0346014-A1 Therapeutic product for the treatment of peri- or postmenopausal conditions ZENECA LIMITED (GB) 1989-12-13 EP claimed
US-4863911-A Method for treating male sexual dysfunction UNIVERSITY OF FLORIDA (US) 1989-09-05 US claimed
EP-0256668-A2 Method for treating male sexual dysfunction UNIVERSITY OF FLORIDA (US) 1988-02-24 EP claimed
EP-0220844-A2 Use of estrogen-dihydropyridine compounds for weight control UNIVERSITY OF FLORIDA (US) 1987-05-06 EP claimed
US-4617298-A STEROIDS UNIVERSITY OF FLORIDA (US) 1986-10-14 US claimed
US-4298594-A BENEFICIAL ALTERATION OF PHARMACODYNAMICS ARTHUR D. LITTLE, INC. (US) 1981-11-03 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230089351-A1 METHODS RELATED TO BIOACTIVE AGENTS THAT CONVERT FROM ANIONS TO MOLECULES FABP2, FABP4, GUSB LMNA 344/4885ESR1 1524/4885SMN1; SMN2 2548/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.