Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.63 |
| ▸ | HTR7 | P34969 | 2/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.58 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.56 |
| ▸ | ADRA1A | P35348 | 3/20 | 0.56 |
| ▸ | ADRA1B | P35368 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5440770 | 0.99 | MAPT (0.65) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5430198 | 0.95 | MAPT (0.67) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5427939 | 0.90 | ADRA1D (0.67) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5438999 | 0.89 | KDM4E (0.67) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5442120 | 0.87 | HTR1A (0.62) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5435824 | 0.87 | KDM4E (0.72) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5430709 | 0.84 | DRD2 (0.57) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5425415 | 0.83 | KDM4E (0.70) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5436548 | 0.83 | SIGMAR1 (0.61) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5427956 | 0.83 | KDM4E (0.73) | MAPTMEN1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0061149-B1 | ALKYLENEDIOXYBENZENE DERIVATIVES AND ACID ADDITION SALTS THEREOF AND A PROCESS FOR THEIR PREPARATION | MITSUBISHI KASEI CORPORATION (JP) | 1984-11-28 | — | — | EP | disclosed |
| EP-0061149-A1 | Alkylenedioxybenzene derivatives and acid addition salts thereof and a process for their preparation | MITSUBISHI KASEI CORPORATION (JP) | 1982-09-29 | — | — | EP | disclosed |