Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.51 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.51 |
| ▸ | HTR1B | P28222 | 2/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.45 |
| ▸ | DRD4 | P21917 | 9/20 | 0.43 |
| ▸ | DRD2 | P14416 | 8/20 | 0.43 |
| ▸ | DRD3 | P35462 | 6/20 | 0.43 |
| ▸ | LDHA | P00338 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11102255 | 0.85 | PIK3CD (0.53) | PIK3CDPIK3R1HTR1BHTR1DHTR7 | |
| SCHEMBL11105081 | 0.83 | DRD2 (0.45) | HTR1BDRD4DRD2DRD3LDHA | |
| SCHEMBL11102959 | 0.83 | PIK3CD (0.51) | PIK3CDPIK3R1HTR1BHTR1DHTR7 | |
| SCHEMBL11105028 | 0.80 | DRD2 (0.47) | HTR1BDRD4DRD2DRD3L3MBTL1 | |
| SCHEMBL11287541 | 0.79 | PPARD (0.40) | LDHAL3MBTL1 | |
| SCHEMBL11104385 | 0.79 | LMNA (0.45) | LDHAL3MBTL1 | |
| SCHEMBL11112404 | 0.79 | PIK3CD (0.53) | PIK3CDPIK3R1HTR1BHTR1DHTR7 | |
| SCHEMBL11107868 | 0.78 | CYP2C19 (0.43) | DRD2LDHA | |
| SCHEMBL11109514 | 0.77 | PIK3CD (0.57) | PIK3CDPIK3R1HTR1BHTR1DHTR7 | |
| SCHEMBL11109296 | 0.76 | SMN1; SMN2 (0.43) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435402-A | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY, LIMITED (JP) | 1984-03-06 | — | — | US | disclosed |
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |