Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.47 |
| ▸ | DRD4 | P21917 | 2/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.40 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11105081 | 0.96 | DRD2 (0.45) | DRD2DRD4DRD3ALDH1A1HTR1B | |
| SCHEMBL11101849 | 0.84 | DRD2 (0.47) | DRD2DRD4DRD3ALDH1A1HTR1B | |
| SCHEMBL11109252 | 0.82 | DRD2 (0.47) | DRD2DRD4DRD3ALDH1A1HTR1B | |
| SCHEMBL11287541 | 0.81 | PPARD (0.40) | ALDH1A1SMN1; SMN2CYP2C19CYP1A2CYP3A4 | |
| SCHEMBL11104385 | 0.81 | LMNA (0.45) | ALDH1A1KMT2AMEN1SMN1; SMN2CYP2C19 | |
| SCHEMBL11109296 | 0.81 | SMN1; SMN2 (0.43) | ALDH1A1KMT2AMEN1SMN1; SMN2BRD4 | |
| SCHEMBL11107868 | 0.80 | CYP2C19 (0.43) | DRD2ALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL11102550 | 0.80 | DRD2 (0.45) | DRD2DRD4DRD3ALDH1A1HTR1B | |
| SCHEMBL11103109 | 0.80 | PIK3CD (0.51) | DRD2DRD4DRD3HTR1BL3MBTL1 | |
| SCHEMBL11255217 | 0.79 | LDHA (0.63) | ALDH1A1KMT2AMEN1SMN1; SMN2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435402-A | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY, LIMITED (JP) | 1984-03-06 | — | — | US | disclosed |
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |