Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 4/20 | 0.49 |
| ▸ | HTR2B | P41595 | 4/20 | 0.49 |
| ▸ | HTR2C | P28335 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | DRD1 | P21728 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.49 |
| ▸ | DRD4 | P21917 | 2/20 | 0.49 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.49 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.49 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11111967 | 0.86 | DRD3 (0.41) | HTR2AHTR2BHTR2CCYP3A4DRD3 | |
| SCHEMBL11106470 | 0.86 | DRD2 (0.46) | HTR2AHTR2BHTR2CCYP3A4DRD3 | |
| SCHEMBL11104065 | 0.84 | DRD2 (0.47) | HTR2AHTR2BHTR2CDRD3DRD1 | |
| SCHEMBL9280480 | 0.81 | HTR2C (0.56) | HTR2AHTR2BHTR2CCYP3A4DRD3 | |
| SCHEMBL2675996 | 0.78 | OPRM1 (0.62) | HTR2AHTR2BHTR2CDRD3DRD1 | |
| SCHEMBL11256455 | 0.77 | P2RX4 (0.48) | CYP3A4MEN1KMT2ADRD2DRD4 | |
| SCHEMBL11258249 | 0.77 | CYP2D6 (0.49) | HTR2AHTR2BHTR2CDRD3DRD1 | |
| SCHEMBL2675787 | 0.75 | HTR2C (0.57) | HTR2AHTR2BHTR2CMEN1KMT2A | |
| SCHEMBL2675247 | 0.74 | HTR2C (0.56) | HTR2AHTR2BHTR2CMEN1KMT2A | |
| SCHEMBL7808866 | 0.73 | OPRM1 (0.41) | HTR2AHTR2BHTR2CCYP3A4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4434171-A | NEUROLEPTIC, ANTIDEPRESSANT | SANDOZ LTD. (CH) | 1984-02-28 | — | — | US | claimed |