Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9049960 | 0.89 | MAPT (0.64) | MAPTTDP1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL2546392 | 0.74 | L3MBTL1 (0.61) | MAPTTDP1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL11659356 | 0.74 | HPGD (0.64) | ALDH1A1LMNARAB9ASMN1; SMN2HPGD | |
| SCHEMBL9609808 | 0.74 | SMN1; SMN2 (0.82) | MAPTALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL9028 | 0.74 | TDP1 (0.60) | MAPTTDP1ALDH1A1LMNAHPGD | |
| SCHEMBL10118277 | 0.73 | SMN1; SMN2 (0.62) | MAPTALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL11662901 | 0.73 | SMN1; SMN2 (0.54) | MAPTALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL15859554 | 0.73 | L3MBTL1 (0.54) | MAPTALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL282531 | 0.72 | SMN1; SMN2 (0.71) | MAPTALDH1A1LMNARAB9ASMN1; SMN2 | |
| SCHEMBL4654049 | 0.72 | TDP1 (0.72) | MAPTTDP1ALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4490551-A | Process for the production of urethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1984-12-25 | — | — | US | disclosed |
| EP-0016948-A1 | Process for preparing urethanes | BAYER AG (DE) | 1980-10-15 | — | — | EP | disclosed |