Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | MEN1 | O00255 | 4/20 | 0.60 |
| ▸ | BLM | P54132 | 1/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 8/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.59 |
| ▸ | HPGD | P15428 | 2/20 | 0.59 |
| ▸ | ATM | Q13315 | 2/20 | 0.59 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11104241 | 0.89 | MAPT (0.51) | MAPTTDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL9028 | 0.84 | TDP1 (0.60) | MAPTTDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL4654049 | 0.82 | TDP1 (0.72) | MAPTTDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL2546392 | 0.78 | L3MBTL1 (0.61) | MAPTTDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL28173861 | 0.78 | TDP1 (0.54) | MAPTTDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL28896841 | 0.78 | TDP1 (1.00) | MAPTTDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11659356 | 0.78 | HPGD (0.64) | ALDH1A1KMT2AMEN1L3MBTL1LMNA | |
| SCHEMBL19712980 | 0.77 | ALDH1A1 (0.50) | MAPTTDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL13846441 | 0.76 | TDP1 (0.59) | MAPTTDP1ALDH1A1KMT2AMEN1 | |
| SCHEMBL11034598 | 0.76 | CYP3A4 (0.60) | MAPTTDP1ALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747355-A1 | NOVEL CARBAMATE DERIVATIVE AND MEDICINAL COMPOSITION CONTAINING THE SAME | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-12-11 | — | — | EP | disclosed |