Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9028 | 0.90 | TDP1 (0.60) | L3MBTL1TDP1ALDH1A1LMNAHPGD | |
| SCHEMBL1568658 | 0.86 | L3MBTL1 (0.61) | L3MBTL1TDP1ALDH1A1LMNAHPGD | |
| SCHEMBL7716853 | 0.85 | L3MBTL1 (0.53) | L3MBTL1TDP1ALDH1A1LMNAHPGD | |
| SCHEMBL28173861 | 0.84 | TDP1 (0.54) | L3MBTL1TDP1ALDH1A1LMNAHPGD | |
| SCHEMBL9049960 | 0.78 | MAPT (0.64) | L3MBTL1TDP1ALDH1A1LMNAHPGD | |
| SCHEMBL11094302 | 0.77 | ALDH1A1 (0.59) | L3MBTL1TDP1ALDH1A1HPGDMAPT | |
| SCHEMBL6037565 | 0.75 | KMT2A (0.59) | L3MBTL1ALDH1A1HPGDKMT2AMEN1 | |
| SCHEMBL28770107 | 0.75 | L3MBTL1 (0.60) | L3MBTL1TDP1ALDH1A1LMNAHPGD | |
| SCHEMBL11076373 | 0.75 | KMT2A (0.58) | TDP1ALDH1A1LMNAHPGDMAPT | |
| SCHEMBL6037499 | 0.75 | ALDH1A1 (0.75) | TDP1ALDH1A1LMNAHPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011121602-A1 | PROCESS FOR PREPARATION OF DIBENZOTHIAZEPINONE COMPOUNDS | HIKAL LIMITED (IN) | 2011-10-06 | — | — | WO | disclosed |
| WO-2011121602-A1 | PROCESS FOR PREPARATION OF DIBENZOTHIAZEPINONE COMPOUNDS | HIKAL LIMITED (IN) | 2011-10-06 | — | — | WO | disclosed |