Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 7/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11062257 | 0.89 | ACE (0.55) | ACEKMT2ALMNAFFAR2HTT | |
| SCHEMBL11219793 | 0.89 | ACE (0.43) | ACELMNAFFAR2HTT | |
| SCHEMBL11104668 | 0.84 | ACE (0.48) | ACELMNAFFAR2 | |
| SCHEMBL11110226 | 0.82 | ACE (0.53) | ACEKMT2AFFAR2 | |
| SCHEMBL11104269 | 0.81 | LMNA (0.46) | ACEKMT2ALMNAFFAR2HTT | |
| SCHEMBL11068373 | 0.79 | KMT2A (0.50) | ACEKMT2AFFAR2 | |
| SCHEMBL11104679 | 0.79 | ACE (0.46) | ACEKMT2ALMNAFFAR2HTT | |
| SCHEMBL11194036 | 0.78 | ACE (0.59) | ACELMNAFFAR2HTT | |
| SCHEMBL11248462 | 0.78 | KMT2A (0.49) | ACEKMT2AFFAR2 | |
| SCHEMBL11169739 | 0.78 | ACE (0.49) | ACEKMT2ALMNAFFAR2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4457935-A | ANGIOTENSIN-CONVERTING ENZYME INHIBITOR | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1984-07-03 | — | — | US | claimed |