Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11101246 | 0.84 | MAOA (0.48) | MAOAPTGS1MTNR1AMTNR1BGBA1 | |
| SCHEMBL11105590 | 0.79 | MAOA (0.48) | MAOAPTGS1MTNR1AMTNR1BGBA1 | |
| SCHEMBL11105460 | 0.79 | GALR3 (0.54) | LMNARAB9A | |
| SCHEMBL11104537 | 0.77 | PIK3CD (0.56) | MTNR1AMTNR1BALDH1A1DRD3PIK3CD | |
| SCHEMBL11105703 | 0.76 | EGFR (0.52) | LMNAKDM4E | |
| SCHEMBL11256846 | 0.75 | NR2F2 (0.59) | MAOAPTGS1GBA1LMNAKMT2A | |
| SCHEMBL11112352 | 0.74 | MAOA (0.48) | MAOAPTGS1MTNR1AMTNR1BGBA1 | |
| SCHEMBL11108426 | 0.74 | MAOA (0.48) | MAOAPTGS1MTNR1AMTNR1BGBA1 | |
| SCHEMBL11103467 | 0.73 | EGFR (0.46) | PIK3CDKDM4E | |
| SCHEMBL11103433 | 0.72 | ADRB2 (0.44) | MTNR1AMTNR1BMEN1KMT2ADRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435402-A | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY, LIMITED (JP) | 1984-03-06 | — | — | US | disclosed |
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |