Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.33 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.31 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL109610 | 0.89 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2APEX1KDM5AKDM4C | |
| SCHEMBL159564 | 0.88 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2APEX1KDM5AKDM4C | |
| SCHEMBL112128 | 0.86 | ALDH1A1 (0.46) | ALDH1A1APEX1KDM5AKDM4CKDM4E | |
| SCHEMBL109196 | 0.83 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2KDM4EKMT2AGAA | |
| SCHEMBL108355 | 0.82 | DNM1 (0.42) | ALDH1A1SMN1; SMN2APEX1KDM4EDNM1 | |
| SCHEMBL11436694 | 0.82 | DNM1 (0.42) | ALDH1A1SMN1; SMN2APEX1KDM4EDNM1 | |
| SCHEMBL12417820 | 0.82 | SMN1; SMN2 (0.35) | ALDH1A1SMN1; SMN2APEX1KDM4E | |
| SCHEMBL109865 | 0.79 | ZDHHC20 (0.52) | ALDH1A1KDM5AKDM4CKDM4EDNM1 | |
| SCHEMBL329290 | 0.78 | ALDH1A1 (0.44) | ALDH1A1SMN1; SMN2APEX1KDM4EDNM1 | |
| SCHEMBL14642043 | 0.77 | SMN1; SMN2 (0.46) | ALDH1A1SMN1; SMN2APEX1KMT2AZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2424491-A2 | FILM FORMER IN HAIR DYES | Henkel AG & Co. KGaA (DE) | 2012-03-07 | — | — | EP | disclosed |
| WO-2010124897-A2 | FILM FORMER IN HAIR DYES | HENKEL AG & CO. KGAA (DE) | 2010-11-04 | — | — | WO | disclosed |