Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBK1 | Q9UHD2 | 6/20 | 0.48 |
| ▸ | IKBKE | Q14164 | 3/20 | 0.48 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.39 |
| ▸ | CDK9 | P50750 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.33 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.33 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11367261 | 0.84 | NT5E (0.45) | MAPTNPC1RAB9AGFERSMN1; SMN2 | |
| SCHEMBL11375422 | 0.82 | GPR35 (0.46) | MAPTNPC1RAB9AGFERSMN1; SMN2 | |
| SCHEMBL11354192 | 0.81 | TBK1 (0.37) | TBK1IKBKEMAPTNPC1RAB9A | |
| SCHEMBL11107442 | 0.81 | TBK1 (0.51) | TBK1IKBKEMAPTNPC1RAB9A | |
| SCHEMBL11544885 | 0.79 | TBK1 (0.72) | TBK1IKBKENPC1RAB9AKDM4E | |
| SCHEMBL7028933 | 0.76 | TBK1 (0.39) | TBK1IKBKESMN1; SMN2KDM4EKMT2A | |
| SCHEMBL11378177 | 0.76 | TBK1 (0.52) | TBK1IKBKECCNT1CDK9MAPT | |
| SCHEMBL11101370 | 0.69 | TBK1 (0.42) | TBK1IKBKENPC1RAB9AKDM4E | |
| SCHEMBL7024714 | 0.69 | KDM4E (0.41) | CCNT1CDK9MAPTNPC1RAB9A | |
| SCHEMBL6206714 | 0.68 | NPC1 (0.53) | TBK1IKBKEMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4255576-A | 1-Azaxanthone derivatives | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-03-10 | — | — | US | claimed |