Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | PPOX | P50336 | 1/20 | 0.47 |
| ▸ | DTYMK | P23919 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MITF | O75030 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.38 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.38 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9120594 | 0.89 | MEN1 (0.52) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL31118239 | 0.84 | MEN1 (0.55) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11301759 | 0.84 | MEN1 (0.44) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11190333 | 0.80 | TDP1 (0.43) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11810710 | 0.79 | MEN1 (0.44) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10430085 | 0.79 | TDP1 (0.43) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL11213666 | 0.78 | TDP1 (0.57) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10658377 | 0.78 | TDP1 (0.57) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL10495360 | 0.77 | TDP1 (0.41) | TDP1MEN1KMT2ATTRPPOX | |
| SCHEMBL3892796 | 0.77 | TDP1 (0.50) | TDP1MEN1KMT2ATTRPPOX |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435588-A | 2'-CHLORO-4'-TRIFLUOROMETHYL-PHENOXY-3-BENZOATE DERIVATIVES | GAF CORPORATION (US) | 1984-03-06 | — | — | US | disclosed |