Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11106616 | 0.79 | HSD11B1 (0.36) | SMN1; SMN2HTTKMT2ANPC1CCR2 | |
| SCHEMBL11106242 | 0.75 | LMNA (0.36) | HTTMEN1KMT2AALDH1A1PDE4A | |
| SCHEMBL11107877 | 0.74 | LMNA (0.37) | MEN1KMT2APTGS1LMNACA12 | |
| SCHEMBL11105280 | 0.71 | CA9 (0.33) | SMN1; SMN2MEN1KMT2AALDH1A1CYP3A4 | |
| SCHEMBL11110284 | 0.71 | HTT (0.43) | SMN1; SMN2HTTEPHX2MEN1KMT2A | |
| SCHEMBL11105717 | 0.70 | TAAR1 (0.37) | MEN1KMT2AALDH1A1PDE3ACCR2 | |
| SCHEMBL9730858 | 0.69 | OPRK1 (0.36) | HTTMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL5953675 | 0.67 | CA2 (0.37) | KCNH2CA2 | |
| SCHEMBL10576793 | 0.65 | TBXA2R (0.51) | SMN1; SMN2HTTEPHX2MEN1KMT2A | |
| SCHEMBL11108198 | 0.65 | MEN1 (0.39) | SMN1; SMN2MEN1KMT2AMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4456470-A | Herbicidal 2-(alpha-chloromethylsulfonyl) pyridine-1-oxides | UNIROYAL, INC. (US) | 1984-06-26 | — | — | US | disclosed |
| US-4360677-A | Herbicidal 2-(alpha-chloromethylsulfonyl) pyridine-1-oxides | UNIROYAL, INC. (US) | 1982-11-23 | — | — | US | disclosed |