Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11113470 | 0.79 | KMT2A (0.45) | HTTLMNANPSR1MAPTNPC1 | |
| SCHEMBL11108148 | 0.77 | CYP1A2 (0.45) | HTTLMNANPSR1NPC1RAB9A | |
| SCHEMBL10837781 | 0.76 | CYP19A1 (0.57) | CYP19A1TDP1HTTLMNATSHR | |
| SCHEMBL4747589 | 0.72 | HTT (0.53) | CYP19A1HTTLMNANPSR1L3MBTL1 | |
| SCHEMBL5873436 | 0.71 | HTT (0.53) | CYP19A1HTTLMNANPSR1L3MBTL1 | |
| SCHEMBL11036227 | 0.70 | CA2 (0.45) | CYP19A1TSHRHPGDL3MBTL1NPC1 | |
| SCHEMBL8700459 | 0.70 | CYP19A1 (0.78) | CYP19A1 | |
| SCHEMBL30778197 | 0.69 | CYP19A1 (0.39) | CYP19A1TDP1TSHRHPGDMAPT | |
| SCHEMBL7020533 | 0.68 | CYP19A1 (0.56) | CYP19A1HTTLMNANPSR1TSHR | |
| SCHEMBL4747594 | 0.68 | HTT (0.50) | CYP19A1HTTLMNANPSR1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4485112-A | N-[(Benzofuran-2-yl)(phenyl)methyl]-alkylene diamines useful in treating arrhythmic, histaminic and tussive conditions | A. MENARINI S.A.S. (IT) | 1984-11-27 | — | — | US | disclosed |