Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11113470 | 0.89 | KMT2A (0.45) | CYP1A2CYP3A4CYP2C19MEN1KMT2A | |
| SCHEMBL11108233 | 0.77 | CYP19A1 (0.52) | MEN1KMT2ALMNANPC1ALDH1A1 | |
| SCHEMBL10839350 | 0.70 | RAB9A (0.59) | CYP1A2CYP3A4CYP2C19ADORA3ADORA2A | |
| SCHEMBL11106019 | 0.69 | LMNA (0.46) | ADORA2AADORA1MEN1KMT2ALMNA | |
| SCHEMBL2649753 | 0.69 | KMT2A (0.59) | CYP1A2CYP3A4CYP2C19ADORA3ADORA2A | |
| SCHEMBL11107208 | 0.69 | DRD2 (0.47) | CYP1A2CYP3A4CYP2C19ADORA3ADORA2A | |
| SCHEMBL11683231 | 0.66 | MAOB (0.50) | CYP1A2CYP3A4CYP2C19ADORA3ADORA2A | |
| SCHEMBL11683229 | 0.66 | MAOB (0.50) | CYP1A2CYP3A4CYP2C19ADORA3ADORA2A | |
| SCHEMBL6621621 | 0.66 | LMNA (0.54) | CYP1A2CYP3A4CYP2C19ADORA3ADORA2A | |
| SCHEMBL21033125 | 0.65 | RXFP1 (0.81) | ADORA3ADORA2AADORA1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4485112-A | N-[(Benzofuran-2-yl)(phenyl)methyl]-alkylene diamines useful in treating arrhythmic, histaminic and tussive conditions | A. MENARINI S.A.S. (IT) | 1984-11-27 | — | — | US | disclosed |