Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.45 |
| ▸ | MEN1 | O00255 | 6/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11108148 | 0.89 | CYP1A2 (0.45) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11106019 | 0.80 | LMNA (0.46) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11108233 | 0.79 | CYP19A1 (0.52) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL10069982 | 0.70 | LMNA (0.65) | KMT2AMEN1SMN1; SMN2LMNAHTT | |
| SCHEMBL5722855 | 0.69 | KMT2A (0.55) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11887407 | 0.68 | LMNA (0.54) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11107533 | 0.67 | RAB9A (0.79) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL978037 | 0.66 | LMNA (0.77) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL13607694 | 0.66 | LMNA (0.51) | KMT2AMEN1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL4747589 | 0.66 | HTT (0.53) | KMT2AMEN1SMN1; SMN2LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4485112-A | N-[(Benzofuran-2-yl)(phenyl)methyl]-alkylene diamines useful in treating arrhythmic, histaminic and tussive conditions | A. MENARINI S.A.S. (IT) | 1984-11-27 | — | — | US | disclosed |