Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | ERN1 | O75460 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3453355 | 0.85 | LMNA (0.52) | KDM4EALOX15HSD17B10MEN1KMT2A | |
| SCHEMBL3842938 | 0.82 | ERN1 (0.56) | MAPTALDH1A1KDM4ECYP3A4ALOX15 | |
| SCHEMBL3314184 | 0.79 | LMNA (0.51) | MAPTALDH1A1CYP3A4MEN1KMT2A | |
| SCHEMBL5556434 | 0.76 | LMNA (0.57) | KDM4EMEN1KMT2AERN1LMNA | |
| SCHEMBL2559051 | 0.75 | MAPT (0.71) | MAPTALDH1A1KDM4ECYP3A4ALOX15 | |
| SCHEMBL7285643 | 0.74 | PTGDR2 (0.50) | ALDH1A1ALOX15HSD17B10LMNAPOLB | |
| SCHEMBL213877 | 0.73 | PTPN7 (0.51) | MAPTALDH1A1ALOX15HSD17B10MEN1 | |
| SCHEMBL2698893 | 0.73 | MEN1 (0.61) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL20786937 | 0.72 | ALDH1A1 (0.53) | MAPTALDH1A1KDM4ECYP3A4ALOX15 | |
| SCHEMBL31429026 | 0.72 | ALDH1A1 (0.54) | ALDH1A1CYP3A4MEN1KMT2AERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103197-A1 | Acidic O-nitroaromatics as photoinhibitors of polymerization in positive working films | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-03-21 | — | — | EP | disclosed |