Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | PTPRB | P23467 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.40 |
| ▸ | CD69 | Q07108 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3453355 | 0.88 | LMNA (0.52) | PTGDR2ALOX15TSHRHSD17B10HPGD | |
| SCHEMBL5556434 | 0.85 | LMNA (0.57) | PTGDR2LMNAPOLBSMN1; SMN2 | |
| SCHEMBL19617328 | 0.80 | PTGDR2 (0.47) | PTGDR2ALOX15ALDH1A1TSHRPTPN7 | |
| SCHEMBL4416927 | 0.80 | MCL1 (0.50) | PTGDR2ALOX15ALDH1A1TSHRPTPN7 | |
| SCHEMBL8791845 | 0.80 | HPGD (0.57) | ALOX15ALDH1A1PTPN7HSD17B10HPGD | |
| SCHEMBL10661687 | 0.79 | PTGDR2 (0.66) | PTGDR2ALOX15ALDH1A1HSD17B10HPGD | |
| SCHEMBL31562188 | 0.79 | ERN1 (0.67) | PTGDR2LMNAPOLBSMN1; SMN2 | |
| SCHEMBL31562314 | 0.79 | L3MBTL1 (0.51) | PTGDR2LMNASMN1; SMN2GLAL3MBTL1 | |
| SCHEMBL7284155 | 0.77 | PTGDR2 (0.63) | PTGDR2ALOX15ALDH1A1TSHRPTPN7 | |
| SCHEMBL28645298 | 0.77 | ALOX15 (0.65) | ALOX15ALDH1A1TSHRPTPN7HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4760064-A | Cardiotonic agent | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1988-07-26 | — | — | US | disclosed |
| EP-0187322-A1 | Carbostyril compounds, compositions containing same and processes for preparing same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-07-16 | — | — | EP | disclosed |