Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | ERN1 | O75460 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | PTPRB | P23467 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARD | Q03181 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5556434 | 0.90 | LMNA (0.57) | LMNAERN1POLBSMN1; SMN2MEN1 | |
| SCHEMBL7285643 | 0.88 | PTGDR2 (0.50) | LMNAPOLBSMN1; SMN2HSD17B10ALOX15 | |
| SCHEMBL31429026 | 0.85 | ALDH1A1 (0.54) | LMNAERN1POLBMEN1KMT2A | |
| SCHEMBL11109448 | 0.85 | MAPT (0.43) | LMNAERN1POLBSMN1; SMN2MEN1 | |
| SCHEMBL31562634 | 0.83 | KDM4E (0.57) | LMNAERN1POLBSMN1; SMN2MEN1 | |
| SCHEMBL421566 | 0.83 | LMNA (0.49) | LMNAERN1TSHRFFAR1PPARG | |
| SCHEMBL1913198 | 0.81 | PPARA (0.52) | LMNAERN1FFAR1PPARGPPARD | |
| SCHEMBL12049195 | 0.81 | LMNA (0.54) | LMNAPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL4635027 | 0.81 | LMNA (0.54) | LMNAPOLBSMN1; SMN2MEN1KMT2A | |
| SCHEMBL3292757 | 0.80 | ALDH1A1 (0.63) | LMNAPOLBSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166696-B2 | Solid phase synthesis supports and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-01-23 | — | — | US | claimed |
| US-20040265899-A1 | Solid phase synthesis supports and methods | 3M INNOVATIVE PROPERTIES COMPANY | 2004-12-30 | — | — | US | claimed |
| US-6787635-B2 | azlactone-functionalized support such as a crosslinked polymer containing an alkenyl azlactone; use making combinatorial libraries | 3M INNOVATIVE PROPERTIES COMPANY | 2004-09-07 | — | — | US | claimed |
| EP-1373167-A2 | SOLID PHASE SYNTHESIS SUPPORTS AND METHODS | 3M Innovative Properties Company (US) | 2004-01-02 | — | — | EP | claimed |
| US-20020173051-A1 | Solid phase synthesis supports and methods | 3M INNOVATIVE PROPERTIES COMPANY | 2002-11-21 | — | — | US | claimed |
| WO-2002081078-A2 | SOLID PHASE SYNTHESIS SUPPORTS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2002-10-17 | — | — | WO | claimed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-7820785-B2 | Solid phase synthesis supports and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2010-10-26 | — | — | US | disclosed |
| US-20070049728-A1 | SOLID PHASE SYNTHESIS SUPPORTS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY | 2007-03-01 | — | — | US | disclosed |
| US-7166696-B2 | Solid phase synthesis supports and methods | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2007-01-23 | — | — | US | disclosed |
| US-20040265899-A1 | Solid phase synthesis supports and methods | 3M INNOVATIVE PROPERTIES COMPANY | 2004-12-30 | — | — | US | disclosed |
| US-6787635-B2 | azlactone-functionalized support such as a crosslinked polymer containing an alkenyl azlactone; use making combinatorial libraries | 3M INNOVATIVE PROPERTIES COMPANY | 2004-09-07 | — | — | US | disclosed |
| EP-1373167-A2 | SOLID PHASE SYNTHESIS SUPPORTS AND METHODS | 3M Innovative Properties Company (US) | 2004-01-02 | — | — | EP | disclosed |
| US-20020173051-A1 | Solid phase synthesis supports and methods | 3M INNOVATIVE PROPERTIES COMPANY | 2002-11-21 | — | — | US | disclosed |
| WO-2002081078-A2 | SOLID PHASE SYNTHESIS SUPPORTS AND METHODS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2002-10-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020173051-A1 | Solid phase synthesis supports and methods | FES, LSS, CCNK | LMNA 1506/4885ERN1 1000/4885POLB 483/4885 |
| US-20040265899-A1 | Solid phase synthesis supports and methods | FES, LSS, CCNK | LMNA 1506/4885ERN1 1000/4885POLB 483/4885 |
| US-20070049728-A1 | SOLID PHASE SYNTHESIS SUPPORTS AND METHODS | FES, LSS, CCNK | LMNA 1506/4885ERN1 1000/4885POLB 483/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.