Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | KLK7 | P49862 | 1/20 | 0.49 |
| ▸ | KLK14 | Q9P0G3 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.46 |
| ▸ | TUBB | P07437 | 1/20 | 0.46 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.46 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.46 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.46 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.46 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4815855 | 0.87 | KDM4E (0.53) | CYP19A1ALDH1A1MAPTTSHRKLK7 | |
| SCHEMBL13028396 | 0.87 | FAAH (0.46) | CYP19A1ALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL9807751 | 0.86 | CYP19A1 (0.46) | CYP19A1MAPTTBXAS1 | |
| SCHEMBL18280922 | 0.84 | HTT (0.63) | ALDH1A1MAPTTSHRKMT2AGAA | |
| SCHEMBL11106769 | 0.81 | MAOB (0.46) | CYP19A1ALDH1A1KMT2ACES2CES1 | |
| SCHEMBL13028408 | 0.81 | ADH5 (0.51) | CYP19A1ALDH1A1MAPTTSHRSLC6A7 | |
| SCHEMBL31388182 | 0.80 | CYP19A1 (0.52) | CYP19A1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL29238940 | 0.80 | MAOB (0.45) | CYP19A1ALDH1A1KMT2ACES2CES1 | |
| SCHEMBL22242602 | 0.80 | ELANE (0.50) | CYP19A1MAPTKMT2ATBXAS1LMNA | |
| SCHEMBL12569289 | 0.80 | CYP19A1 (0.51) | CYP19A1ALDH1A1MAPTTSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4469865-A | INHIBITORS OF THROMBOXANE SYNTHETASE | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 1984-09-04 | — | — | US | disclosed |
| EP-0076140-A2 | 1,3-Disubstituted imidazoles and a process for their production | Kissei Pharmaceutical Co. Ltd. (JP) | 1983-04-06 | — | — | EP | disclosed |