Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.61 |
| ▸ | MEN1 | O00255 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.61 |
| ▸ | NPC1 | O15118 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | NSD2 | O96028 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | RAF1 | P04049 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | S100A4 | P26447 | 2/20 | 0.41 |
| ▸ | PRKDC | P78527 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14983914 | 0.76 | MAPT (1.00) | KMT2AMEN1MAPTL3MBTL1NPC1 | |
| SCHEMBL14983925 | 0.73 | L3MBTL1 (0.82) | KMT2AMEN1MAPTL3MBTL1NPC1 | |
| SCHEMBL2403872 | 0.70 | POLB (0.51) | KMT2AMEN1LMNAALDH1A1HSD17B10 | |
| SCHEMBL2552173 | 0.70 | MGLL (0.53) | TDP1ALDH1A1ATM | |
| SCHEMBL1239433 | 0.70 | MEN1 (0.55) | KMT2AMEN1MAPTL3MBTL1NPC1 | |
| SCHEMBL15362290 | 0.69 | HTR7 (0.62) | KMT2AMEN1MAPTL3MBTL1NPC1 | |
| SCHEMBL9424119 | 0.69 | LMNA (0.62) | KMT2AMEN1MAPTL3MBTL1NPC1 | |
| SCHEMBL14983920 | 0.69 | MAPT (0.77) | KMT2AMEN1MAPTL3MBTL1NPC1 | |
| SCHEMBL28589473 | 0.68 | MEN1 (0.52) | KMT2AMEN1MAPTL3MBTL1NPC1 | |
| SCHEMBL30775261 | 0.68 | L3MBTL1 (0.52) | KMT2AMEN1MAPTL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0099614-A2 | Nitro, amino and aroylamino-N-phenylpyridinamines and their use in a process for preparing pyrido(1,4)benzodiazapines | A.H. ROBINS COMPANY, INCORPORATED (US) | 1984-02-01 | — | — | EP | claimed |