Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 3/20 | 0.68 |
| ▸ | MEN1 | O00255 | 3/20 | 0.68 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.68 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.68 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.68 |
| ▸ | LMNA | P02545 | 2/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.68 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.68 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.68 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.68 |
| ▸ | PGR | P06401 | 1/20 | 0.68 |
| ▸ | HTR1A | P08908 | 1/20 | 0.68 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.68 |
| ▸ | AR | P10275 | 1/20 | 0.68 |
| ▸ | MAPT | P10636 | 1/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11106473 | 0.84 | AKR1C3 (0.67) | TTRMEN1PTGS2AKR1C3KMT2A | |
| SCHEMBL28286415 | 0.84 | MEN1 (0.51) | TTRMEN1PTGS2AKR1C3KMT2A | |
| SCHEMBL14234727 | 0.83 | AKR1C3 (0.58) | TTRMEN1PTGS2AKR1C3KMT2A | |
| SCHEMBL3064448 | 0.82 | TTR (0.73) | TTRMEN1PTGS2AKR1C3KMT2A | |
| Tolfenamic Acid SCHEMBL25190 | 0.81 | MT-CO2 (1.00) | TTRMEN1PTGS2AKR1C3KMT2A | |
| Tolfenamic Acid SCHEMBL8060884 | 0.81 | MT-CO2 (1.00) | TTRMEN1PTGS2AKR1C3KMT2A | |
| Tolfenamic Acid SCHEMBL29389998 | 0.81 | MT-CO2 (1.00) | TTRMEN1PTGS2AKR1C3KMT2A | |
| Tolfenamic Acid SCHEMBL29484181 | 0.81 | MT-CO2 (1.00) | TTRMEN1PTGS2AKR1C3KMT2A | |
| Meclofenamic Acid SCHEMBL106 | 0.81 | PTGS2 (1.00) | TTRMEN1PTGS2AKR1C3KMT2A | |
| Meclofenamic Acid SCHEMBL11543781 | 0.81 | PTGS2 (1.00) | TTRMEN1PTGS2AKR1C3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4447453-A | 2,2'-IMINODIBENZOIC ACID | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 1984-05-08 | — | — | US | claimed |
| US-4092426-A | LIVER DISORDERS | CHUGAI SEIYAKU KABUSHIKI KAISHA (JA) | 1978-05-30 | — | — | US | disclosed |