Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | CES1 | P23141 | 2/20 | 0.34 |
| ▸ | DGKA | P23743 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | PAM | P19021 | 2/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | KDM6B | O15054 | 1/20 | 0.32 |
| ▸ | KDM5C | P41229 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.32 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.32 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3514262 | 0.79 | DNM1 (0.40) | TSHRALDH1A1LMNACES1DGKA | |
| SCHEMBL11111063 | 0.78 | HCAR2 (0.42) | TSHRALDH1A1HPGDCES2FAAH | |
| SCHEMBL8630003 | 0.76 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL8503383 | 0.72 | KDM6B (0.58) | TSHRALDH1A1LMNACES1DGKA | |
| SCHEMBL11105630 | 0.72 | HCAR2 (0.37) | TSHRALDH1A1HPGDHCAR2ATM | |
| SCHEMBL11110109 | 0.71 | ALDH1A1 (0.38) | TSHRALDH1A1LMNAHCAR2 | |
| SCHEMBL11038420 | 0.70 | — | — | |
| SCHEMBL19171462 | 0.69 | TSHR (0.46) | TSHRALDH1A1LMNACES1DGKA | |
| SCHEMBL9478183 | 0.68 | DGKA (0.52) | TSHRALDH1A1LMNACES1DGKA | |
| SCHEMBL17466647 | 0.68 | TSHR (0.42) | TSHRALDH1A1HPGDFAAHHCAR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0103895-A2 | Novel hydroxylamine derivatives, production and use thereof | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1984-03-28 | — | — | EP | disclosed |