Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 4/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11105709 | 0.69 | OPRD1 (0.42) | OPRD1OPRM1ALDH1A1 | |
| SCHEMBL18203509 | 0.68 | MEN1 (0.34) | MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL23466917 | 0.64 | KDM4E (0.37) | MEN1ALDH1A1KMT2A | |
| SCHEMBL5923194 | 0.63 | L3MBTL3 (0.55) | — | |
| SCHEMBL11308566 | 0.62 | CHRNB4 (0.40) | ALDH1A1 | |
| SCHEMBL9367075 | 0.60 | SLC6A3 (0.46) | SLC6A3MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL27772049 | 0.60 | SLC6A3 (0.46) | SLC6A3MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL27772055 | 0.60 | SLC6A3 (0.46) | SLC6A3MEN1ALDH1A1LMNAKMT2A | |
| SCHEMBL6784455 | 0.60 | HIF1A (0.54) | CYP2C19MEN1ALDH1A1KMT2A | |
| SCHEMBL254670 | 0.59 | HIF1A (0.53) | CYP2C19MEN1ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4479007-A | Chroman-4-ones and process for preparing same | BAYER AKTIENGESELLSCHAFT (DE) | 1984-10-23 | — | — | US | disclosed |
| US-4415741-A | REACTING O-HYDROXYACETOPHENONE AND CYCLOPENTANONE | BAYER AKTIENGESELLSCHAFT (DE) | 1983-11-15 | — | — | US | disclosed |