SCHEMBL254670

SCHEMBL254670

COC(=O)C(C)c1ccc(N2CCCCCC2)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HIF1A Q16665 4/20 0.53
MAPT P10636 7/20 0.51
ALDH1A1 P00352 4/20 0.51
NPSR1 Q6W5P4 1/20 0.51
GFER P55789 3/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C19 P33261 1/20 0.50
SMN1; SMN2 Q16637 4/20 0.48
KDM4E B2RXH2 2/20 0.48
TP53 P04637 2/20 0.48
HPGD P15428 1/20 0.48
KMT2A Q03164 4/20 0.47
MEN1 O00255 2/20 0.47
GAA P10253 1/20 0.47
HTT P42858 1/20 0.47
CCNA2 P20248 2/20 0.46
CDK2 P24941 2/20 0.46
CCNA1 P78396 2/20 0.46
NPC1 O15118 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6784455 0.98 HIF1A (0.54) HIF1AMAPTALDH1A1NPSR1GFER
SCHEMBL5923194 0.87 L3MBTL3 (0.55) HIF1ACCNA2CDK2CCNA1
SCHEMBL21439780 0.84 L3MBTL1 (0.48) MAPTALDH1A1GFERSMN1; SMN2KDM4E
SCHEMBL27565323 0.83 ALDH1A1 (0.53) HIF1AMAPTALDH1A1NPSR1GFER
SCHEMBL27602621 0.82 ALDH1A1 (0.51) HIF1AMAPTALDH1A1NPSR1GFER
SCHEMBL28745217 0.82 MAPT (0.54) HIF1AMAPTALDH1A1NPSR1GFER
SCHEMBL6787925 0.80 MAPT (0.53) HIF1AMAPTALDH1A1NPSR1GFER
SCHEMBL10085476 0.79 RAB9A (0.53) MAPTALDH1A1CYP3A4CYP2C19SMN1; SMN2
SCHEMBL11370742 0.79 CHRM1 (0.54) HIF1AALDH1A1NPSR1SMN1; SMN2KDM4E
SCHEMBL21435774 0.78 MAPT (0.57) MAPTALDH1A1NPSR1CYP2C19SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120058418-A1 THREE-DIMENSIONAL HOLOGRAPHIC DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2012-03-08 US disclosed
WO-2010141323-A1 THREE-DIMENSIONAL HOLOGRAPHIC DISPLAY DEVICE NITTO DENKO CORPORATION (JP) 2010-12-09 WO disclosed