Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 6/20 | 0.59 |
| ▸ | MGLL | Q99685 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | CPS1 | P31327 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CPB1 | P15086 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17938078 | 0.86 | HSD11B1 (0.60) | HSD11B1MGLLKMT2ACPS1CYP2C9 | |
| SCHEMBL6661943 | 0.84 | HSD11B1 (0.55) | HSD11B1MGLLKMT2ACPS1EPHX2 | |
| Hydrochloric Acid SCHEMBL10395819 | 0.83 | HSD11B1 (0.53) | HSD11B1MGLLKMT2ACPS1EPHX2 | |
| SCHEMBL1838212 | 0.82 | MEN1 (0.61) | HSD11B1KMT2ACPS1MEN1 | |
| SCHEMBL9865846 | 0.82 | ALDH1A1 (0.55) | HSD11B1KMT2ALMNAMEN1 | |
| SCHEMBL9377960 | 0.82 | CCR6 (0.58) | HSD11B1MGLLKMT2AKDM4EMEN1 | |
| SCHEMBL718095 | 0.82 | CES2 (0.56) | HSD11B1MGLLKMT2ACYP2C9CYP2C19 | |
| SCHEMBL29591363 | 0.82 | CES2 (0.56) | HSD11B1MGLLKMT2ACYP2C9CYP2C19 | |
| SCHEMBL11619437 | 0.81 | CPS1 (0.56) | HSD11B1MGLLKMT2ACPS1MEN1 | |
| SCHEMBL15566640 | 0.81 | STS (0.54) | HSD11B1MGLLKMT2AKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4432984-A | Anti-hypertensive benzodioxan derivatives | Bouchara, Emile (FR) | 1984-02-21 | — | — | US | disclosed |