Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
| ▸ | CA9 | Q16790 | 2/20 | 0.48 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | SFRP1 | Q8N474 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10462102 | 0.90 | CYP4F2 (0.51) | CA12CA9CA1CA2SFRP1 | |
| SCHEMBL11369869 | 0.86 | TBXA2R (0.55) | ALDH1A1TSHRNPSR1SMN1; SMN2TBXA2R | |
| SCHEMBL11107041 | 0.85 | TBXA2R (0.58) | CA1CA2ALDH1A1LMNAHTT | |
| SCHEMBL11105698 | 0.85 | TBXA2R (0.56) | CA12CA9CA1CA2SFRP1 | |
| SCHEMBL11113227 | 0.80 | CYP4Z1 (0.48) | CA12CA9ALDH1A1LMNACYP4Z1 | |
| SCHEMBL11109071 | 0.80 | ALDH1A1 (0.69) | ALDH1A1LMNAKDM4ETSHRHSD17B10 | |
| SCHEMBL411161 | 0.80 | SFRP1 (0.66) | SFRP1ALDH1A1HSD17B10HTTNPSR1 | |
| SCHEMBL28331917 | 0.80 | CA12 (0.49) | CA12CA9ALDH1A1HSD17B10TDP1 | |
| SCHEMBL11111137 | 0.79 | L3MBTL1 (0.51) | CA12CA9ALDH1A1LMNAL3MBTL1 | |
| SCHEMBL27463180 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KDM4ENPSR1L3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4443477-A | ANTICOAGULANTS, ANTILIPEMIC AGENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1984-04-17 | — | — | US | disclosed |