Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.52 |
| ▸ | CES1 | P23141 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 6/20 | 0.52 |
| ▸ | CA2 | P00918 | 6/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | PARP4 | Q9UKK3 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8676355 | 0.74 | CA1 (0.47) | CES2CES1CA1CA2MAPK1 | |
| P-Methoxy-Acetophenone SCHEMBL6350575 | 0.71 | MAPT (0.61) | CES2CES1CA1CA2HPGD | |
| SCHEMBL7338845 | 0.71 | CA2 (0.43) | CES2CES1CA1CA2HPGD | |
| SCHEMBL247019 | 0.70 | CA1 (0.75) | CES2CES1CA1CA2PARP10 | |
| SCHEMBL51509 | 0.69 | RXFP1 (0.79) | CES2CES1CA1CA2HPGD | |
| SCHEMBL14507040 | 0.69 | CES2 (1.00) | CES2CES1CA1CA2HPGD | |
| SCHEMBL9418310 | 0.69 | RXFP1 (0.79) | CES2CES1CA1CA2HPGD | |
| SCHEMBL557152 | 0.69 | CES2 (1.00) | CES2CES1CA1CA2HPGD | |
| P-Anisic Acid SCHEMBL19510379 | 0.69 | CA1 (0.91) | CES2CES1CA1CA2HPGD | |
| P-Anisic Acid SCHEMBL5969785 | 0.69 | CA1 (0.91) | CES2CES1CA1CA2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044088-B1 | P-METHOXY-BENZOYL DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-02-22 | — | — | EP | disclosed |