Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 1/20 | 0.53 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.53 |
| ▸ | HTR7 | P34969 | 5/20 | 0.51 |
| ▸ | DRD4 | P21917 | 6/20 | 0.49 |
| ▸ | DRD2 | P14416 | 6/20 | 0.49 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.46 |
| ▸ | DRD3 | P35462 | 4/20 | 0.45 |
| ▸ | HTR1B | P28222 | 2/20 | 0.45 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CASP7 | P55210 | 1/20 | 0.43 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9609205 | 0.78 | HTR7 (0.58) | PIK3CDPIK3R1HTR7ALDH1A1CYP1A2 | |
| SCHEMBL16656099 | 0.78 | CYP1A2 (0.54) | ALDH1A1USP2CYP1A2APEX1CYP2C19 | |
| SCHEMBL9608210 | 0.75 | CHRNB2 (0.43) | HTR7ALDH1A1USP2CYP1A2CYP2C19 | |
| SCHEMBL1666072 | 0.74 | CYP1A2 (0.64) | ALDH1A1USP2CYP1A2CYP2C19CASP7 | |
| SCHEMBL29836457 | 0.74 | CYP1A2 (0.64) | ALDH1A1USP2CYP1A2CYP2C19CASP7 | |
| SCHEMBL31240737 | 0.73 | HTR7 (0.57) | PIK3CDPIK3R1HTR7DRD4DRD2 | |
| SCHEMBL29526065 | 0.73 | SMN1; SMN2 (0.47) | ALDH1A1USP2CYP1A2APEX1CYP2C19 | |
| SCHEMBL11306777 | 0.73 | HTR7 (0.51) | PIK3CDPIK3R1HTR7DRD4DRD2 | |
| SCHEMBL21593130 | 0.72 | POLB (0.42) | ALDH1A1CYP1A2CYP2C19CLK4 | |
| SCHEMBL20562358 | 0.72 | CYP1A2 (0.41) | HTR7ALDH1A1USP2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4435402-A | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY, LIMITED (JP) | 1984-03-06 | — | — | US | disclosed |
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |