Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 11/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 9/20 | 0.64 |
| ▸ | CLK4 | Q9HAZ1 | 8/20 | 0.64 |
| ▸ | TSHR | P16473 | 8/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 4/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 2/20 | 0.54 |
| ▸ | NOS2 | P35228 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29836457 | 1.00 | CYP1A2 (0.64) | CYP1A2CYP2D6CLK4TSHRCYP3A4 | |
| SCHEMBL3948180 | 0.85 | CYP1A2 (0.48) | CYP1A2CYP2D6CLK4TSHRCYP3A4 | |
| SCHEMBL30792466 | 0.83 | CYP1A2 (0.47) | CYP1A2CYP2D6CLK4TSHRCYP3A4 | |
| SCHEMBL29192721 | 0.83 | CYP1A2 (0.47) | CYP1A2CYP2D6CLK4TSHRCYP3A4 | |
| SCHEMBL9609205 | 0.83 | HTR7 (0.58) | CYP1A2CYP2D6CLK4TSHRCYP3A4 | |
| SCHEMBL12466337 | 0.83 | CCNT1 (0.57) | CYP1A2CYP2D6CLK4TSHRCYP3A4 | |
| SCHEMBL16654031 | 0.83 | CYP1A2 (0.67) | CYP1A2CYP2D6CLK4TSHRCYP3A4 | |
| SCHEMBL23291905 | 0.82 | ALDH1A1 (0.49) | CYP1A2CYP2D6CLK4TSHRCYP3A4 | |
| SCHEMBL34463057 | 0.80 | MAP4K4 (0.52) | CYP1A2CYP2D6CLK4TSHRCYP3A4 | |
| SCHEMBL1136800 | 0.80 | HTT (0.54) | CYP1A2CYP2D6CLK4TSHRCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119487029-A | N6-adenosyl-methyltransferase PROTAC and methods of use thereof | 苏黎世大学 | 2025-02-18 | — | — | CN | disclosed |
| US-20240139189-A1 | N6-ADENOSINE-METHYLTRANSFERASE INHIBITORS IN CANCER TREATMENT | UNIVERSITY OF ZURICH (CH) | 2024-05-02 | — | — | US | disclosed |
| CN-117715911-A | N6-adenosyl-methyltransferase inhibitors in the treatment of cancer | 苏黎世大学 | 2024-03-15 | — | — | CN | disclosed |
| WO-2023222762-A1 | N6-ADENOSINE-METHYLTRANSFERASE PROTACS AND METHODS OF USE THEREOF | UNIVERSITY OF ZURICH (CH) | 2023-11-23 | — | — | WO | disclosed |
| EP-3807273-B1 | AZAINDOLE DERIVATIVES AS RHO-KINASE INHIBITORS | CHIESI FARM SPA (IT) | 2022-08-03 | — | — | EP | disclosed |
| EP-3421457-B1 | PYRIMIDINE FGFR4 INHIBITORS | EISAI R&D MAN CO LTD (JP) | 2021-10-06 | — | — | EP | disclosed |
| US-20210253568-A1 | AZAINDOLE DERIVATIVES AS RHO-KINASE INHIBITORS | CHIESI FARMACEUTICI S.P.A. (IT) | 2021-08-19 | — | — | US | disclosed |
| US-10912774-B2 | Pyrimidine FGFR4 inhibitors | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2021-02-09 | — | — | US | disclosed |
| US-10912774-B2 | Pyrimidine FGFR4 inhibitors | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2021-02-09 | — | — | US | disclosed |
| US-20200206222-A1 | PYRIMIDINE FGFR4 INHIBITORS | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2020-07-02 | — | — | US | disclosed |
| EP-0370704-B1 | Aralkylamine derivatives, preparation thereof and fungicides containing the same | UBE INDUSTRIES (JP) | 1995-02-01 | — | — | EP | disclosed |
| EP-0264217-B1 | ARALKYLAMINOPYRIMIDINE DERIVATIVE, PROCESS FOR PRODUCING THEREOF AND INSECTICIDE, ACARICIDE AND FUNGICIDE CONTAINING SAID DERIVATIVE AS ACTIVE INGREDIENT | UBE INDUSTRIES, LTD. (JP) | 1993-06-30 | — | — | EP | disclosed |
| US-5141941-A | ARALKYLAMINE DERIVATIVES, AND FUNGICIDES CONTAINING THE SAME | UBE INDUSTRIES, LTD. (JP) | 1992-08-25 | — | — | US | disclosed |
| US-5073558-A | AMINOPYRIMIDINE DERIVATIVE AND INSECTICIDE OR BACTERICIDE CONTAINING THE DERIVATIVE | UBE INDUSTRIES, LTD. (JP) | 1991-12-17 | — | — | US | disclosed |
| US-4985426-A | AGRICULTURAL USE | UBE INDUSTRIES, LTD. (JP) | 1991-01-15 | — | — | US | disclosed |
| EP-0356158-A1 | Aminopyrimidine derivative, process for preparing the derivative, and insecticide or bactericide containing the derivative | UBE INDUSTRIES, LTD. (JP) | 1990-02-28 | — | — | EP | disclosed |
| US-4895849-A | Aralkylaminopyrimidine compounds which are useful as for producing thereof and insecticides | UBE INDUSTRIES, LTD. (JP) | 1990-01-23 | — | — | US | disclosed |
| EP-0264217-A2 | Aralkylaminopyrimidine derivative, process for producing thereof and insecticide, acaricide and fungicide containing said derivative as active ingredient | UBE INDUSTRIES, LTD. (JP) | 1988-04-20 | — | — | EP | disclosed |
| US-4435402-A | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY, LIMITED (JP) | 1984-03-06 | — | — | US | disclosed |
| EP-0057440-A1 | Aminopyrimidine derivatives, processes for their preparation, and fungicidal, insecticidal and acaricidal compositions containing them | SANKYO COMPANY LIMITED (JP) | 1982-08-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10912774-B2 | Pyrimidine FGFR4 inhibitors | FGFR4, FGFR1, FGFR3 | CYP1A2 2976/4885CYP2D6 2060/4885CLK4 2370/4885 |
| US-20240139189-A1 | N6-ADENOSINE-METHYLTRANSFERASE INHIBITORS IN CANCER TREATMENT | NNMT, MTAP, RNMT | CYP1A2 3481/4885CYP2D6 2613/4885CLK4 2489/4885 |
| US-20210253568-A1 | AZAINDOLE DERIVATIVES AS RHO-KINASE INHIBITORS | ROCK1, ROCK2, RHOA | CYP1A2 380/4885CYP2D6 2264/4885CLK4 4157/4885 |
| US-20200206222-A1 | PYRIMIDINE FGFR4 INHIBITORS | FGFR4, FGFR1, FGFR3 | CYP1A2 2976/4885CYP2D6 2060/4885CLK4 2370/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.