Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11118658 | 0.87 | OPRM1 (0.34) | OPRM1 | |
| SCHEMBL11118692 | 0.80 | DPP9 (0.36) | OPRM1P2RX7HTR2C | |
| SCHEMBL10500358 | 0.77 | LMNA (0.40) | OPRM1OPRL1 | |
| SCHEMBL11111810 | 0.73 | SCN4A (0.34) | OPRM1OPRL1HTR2C | |
| SCHEMBL11119015 | 0.69 | OPRM1 (0.35) | OPRM1THRB | |
| SCHEMBL10499523 | 0.67 | KCNH2 (0.43) | OPRM1 | |
| SCHEMBL11117013 | 0.65 | LMNA (0.45) | OPRM1 | |
| SCHEMBL10500844 | 0.64 | ATM (0.45) | — | |
| SCHEMBL11115862 | 0.64 | OPRM1 (0.37) | OPRM1 | |
| SCHEMBL11114005 | 0.64 | MTNR1A (0.43) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121972-A2 | N-aryl-alpha-amino-carboxamides | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-10-17 | — | — | EP | disclosed |