Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 1/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.34 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.30 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.30 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11118656 | 0.84 | OPRM1 (0.37) | SCN4AOPRM1GABRDGABRA1GABRB1 | |
| SCHEMBL11118690 | 0.79 | DPP9 (0.40) | SCN4AOPRM1GABRDGABRA1GABRB1 | |
| SCHEMBL11114336 | 0.77 | KMT2A (0.42) | SCN4AOPRM1GABRDGABRA1GABRB1 | |
| SCHEMBL11114555 | 0.76 | OPRM1 (0.40) | OPRM1MEN1KMT2AOPRD1OPRK1 | |
| SCHEMBL10500358 | 0.74 | LMNA (0.40) | SCN4AOPRM1OPRL1MEN1KMT2A | |
| SCHEMBL11118947 | 0.74 | OPRM1 (0.37) | SCN4AOPRM1GABRDGABRA1GABRB1 | |
| SCHEMBL11111813 | 0.73 | OPRM1 (0.33) | OPRM1OPRL1HTR2C | |
| SCHEMBL11114801 | 0.68 | SCN4A (0.35) | SCN4AOPRM1GABRDGABRA1GABRB1 | |
| SCHEMBL11117599 | 0.68 | LMNA (0.43) | SCN4AOPRM1HTR2C | |
| SCHEMBL11119013 | 0.67 | MEN1 (0.38) | SCN4AOPRM1GABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0121972-A2 | N-aryl-alpha-amino-carboxamides | JANSSEN PHARMACEUTICA N.V. (BE) | 1984-10-17 | — | — | EP | disclosed |