Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 4/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.31 |
| ▸ | HTR2C | P28335 | 5/20 | 0.31 |
| ▸ | PGR | P06401 | 4/20 | 0.31 |
| ▸ | HTR2A | P28223 | 3/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.31 |
| ▸ | DRD2 | P14416 | 2/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
| ▸ | HRH1 | P35367 | 2/20 | 0.31 |
| ▸ | DRD3 | P35462 | 2/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.30 |
| ▸ | AR | P10275 | 2/20 | 0.30 |
| ▸ | STK17B | O94768 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11102607 | 0.87 | PGR (0.32) | ALDH1A1MAPTALOX12SMN1; SMN2HTR2C | |
| SCHEMBL11113392 | 0.85 | HTR2A (0.33) | HTR2CPGRHTR2AHTR2BADRA2A | |
| Hydrochloric Acid SCHEMBL11103844 | 0.84 | MEN1 (0.31) | MAOBHTR2AARSTK17B | |
| SCHEMBL11107045 | 0.81 | MTNR1A (0.38) | ALDH1A1MAPTMAOBROCK2HTR2C | |
| SCHEMBL11109405 | 0.80 | KDM4E (0.38) | ALDH1A1MAPT | |
| SCHEMBL11106440 | 0.79 | ALDH1A1 (0.38) | ALDH1A1MAOBROCK2STK17B | |
| SCHEMBL11105723 | 0.78 | HTR2C (0.38) | ALDH1A1MAPTALOX12SMN1; SMN2MAOB | |
| SCHEMBL11110526 | 0.75 | MAOB (0.35) | ALDH1A1MAPTALOX12SMN1; SMN2MAOB | |
| SCHEMBL11107702 | 0.74 | AR (0.38) | HTR2CPGRHTR2AHTR2BADRA2A | |
| SCHEMBL11106584 | 0.74 | AR (0.39) | ALDH1A1MAPTDRD2DRD3AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4463001-A | ANTIULCER AGENTS | FARMITALIA CARLO ERBA S.P.A. (IT) | 1984-07-31 | — | — | US | disclosed |