Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3724084 | 0.91 | MEN1 (0.41) | NPSR1LMNAHTTHPGDPTGS2 | |
| SCHEMBL8923155 | 0.79 | ALDH1A1 (0.50) | LMNAMAPTCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL21501228 | 0.74 | MAOA (0.45) | MAOAMAOBSMN1; SMN2LMNAPPARA | |
| SCHEMBL10204685 | 0.72 | RAB9A (0.63) | MAOAMAOBSMN1; SMN2LMNAHPGD | |
| SCHEMBL3723944 | 0.72 | CES1 (0.42) | SMN1; SMN2LMNAKMT2AMAPTCYP3A4 | |
| Water SCHEMBL11426874 | 0.72 | KIF11 (0.33) | — | |
| SCHEMBL28567266 | 0.72 | TSHR (0.42) | SMN1; SMN2NPSR1LMNAHTTHPGD | |
| SCHEMBL8922723 | 0.72 | TSHR (0.42) | SMN1; SMN2NPSR1LMNAHTTHPGD | |
| Water SCHEMBL11407563 | 0.72 | KIF11 (0.33) | — | |
| SCHEMBL934888 | 0.71 | ESR1 (0.44) | LMNAHPGDCYP3A4ALDH1A1SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0117378-A1 | 1-Carbonyl-1-phenoxyphenyl-2-azolyl-ethanol-derivatives as microbicides, and their intermediates | CIBA-GEIGY AG (CH) | 1984-09-05 | — | — | EP | disclosed |