Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | PLAU | P00749 | 4/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.44 |
| ▸ | GRK2 | P25098 | 2/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 1/20 | 0.40 |
| ▸ | PLAT | P00750 | 1/20 | 0.40 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11129973 | 0.88 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1KDM4ENSD2MTNR1A | |
| SCHEMBL14058917 | 0.86 | F2R (0.48) | SMN1; SMN2ALDH1A1KDM4ENSD2MTNR1A | |
| SCHEMBL11118240 | 0.85 | MTNR1A (0.50) | SMN1; SMN2ALDH1A1KDM4ENSD2MTNR1A | |
| SCHEMBL11117500 | 0.84 | MTNR1A (0.59) | MTNR1AMTNR1BGRM4NPSR1MAPT | |
| SCHEMBL12862491 | 0.82 | CACNA1B (0.46) | SMN1; SMN2ALDH1A1KDM4ENSD2MTNR1A | |
| SCHEMBL12895716 | 0.79 | HDAC4 (0.48) | SMN1; SMN2ALDH1A1KDM4ENSD2MTNR1A | |
| SCHEMBL11116182 | 0.78 | ALDH1A1 (0.57) | ALDH1A1KDM4EMTNR1AMTNR1BHDAC4 | |
| SCHEMBL10654061 | 0.76 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1PLAUCNR1CA2 | |
| SCHEMBL29678387 | 0.76 | ALDH1A1 (0.67) | SMN1; SMN2ALDH1A1PLAUCNR1CA2 | |
| SCHEMBL10989612 | 0.76 | MTNR1A (0.60) | SMN1; SMN2ALDH1A1MTNR1AMTNR1BNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0058868-B1 | DERIVATIVES OF TETRAHYDROPYRIMIDINON, PROCESS FOR THEIR PREPARATION AND HERBICIDES CONTAINING THOSE DERIVATIVES AS ACTIVE PRODUCTS | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1984-04-11 | — | — | EP | disclosed |
| US-4402731-A | Herbicidally active novel substituted tetrahydropyrimidinones | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1983-09-06 | — | — | US | disclosed |
| EP-0058868-A1 | Derivatives of tetrahydropyrimidinon, process for their preparation and herbicides containing those derivatives as active products | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1982-09-01 | — | — | EP | disclosed |